For HVPS amplitude for wound healing, which is typical?

• A. 60-64
• B. 30-50
• C. 100-150
• D. 200-300

Answer: (C)

High-voltage pulsed current for wound healing relies on delivering a monophasic, pulsed electric field with relatively high voltage to push current through the wound bed and surrounding tissue. The amplitude is chosen to overcome skin and tissue impedance so that enough current density reaches the wound to influence cellular activities that promote repair, such as fibroblast function, collagen deposition, and macrophage activity.

The typical range used in practice is about 100 to 150 volts. This level provides the necessary driving force to achieve therapeutic effects without exceeding safety limits. Lower ranges like 60–64 or 30–50 volts may not generate enough current density at the wound site to produce the desired healing responses. A range as high as 200–300 volts is generally not needed for standard wound healing protocols and is less common in routine treatment.